PhD Position

PhD position – Enzyme-based sensor for biomarker level detection

A prototype enzyme-based biosensor will be developed with potentiostatic readouts complemented by NFC integration to enable rapid and reliable point-of-need applications. Enzymes with high substrate specificity will be selected and immobilized on the electrode surface to facilitate the detection of target compounds via redox reactions. The project will focus on optimizing enzyme stability, selectivity, and signal strength through advanced immobilization strategies and enzyme engineering approaches. A critical challenge—the selectivity for the target compound—will be tackled by implementing a multi-enzyme, multi-electrode setup for comparative analysis. This research aims to advance the development of stable, highly selective biosensors suitable for real-world applications.

Your Tasks

1. Conduct independent research in the field of enzyme technology, including enzyme expression and purification, assay development and analytics, kinetic characterization, enzyme engineering, and enzyme immobilization.
2. Collaborate closely with our industry partner on joint development activities.
3. Document and present your results through various formats, such as scientific reports, publications, oral presentations, and posters.
4. Ensure the professional handling, maintenance, and operation of laboratory equipment.
5. Contribute to acib management tasks and assist in disseminating research findings to the general public.

What We Offer

Join our team at a reputable, nationally and internationally well-connected research center at the forefront of biotechnological innovation. You will be integrated into the academic environment of TU Graz at the Institute of Biotechnology and Biochemical Engineering, working alongside a motivated team of scientists and collaborating with a renowned Austrian industry partner. We are deeply committed to providing scientific guidance and fostering your career development. Through acib and TU Graz, you will have access to numerous opportunities for further education and personal growth. Our flexible working hours and attractive voluntary social benefits—including meal vouchers or public transport tickets—ensure a rewarding and supportive work environment. And not to forget: You make your research visible and broaden your network!

Your Profile

Ideally, you hold a Master’s degree or Diploma from a recognized university in Biotechnology, Biochemistry, (Bio-) Chemical Engineering, or a related field. We are particularly interested in candidates with the following skills and experiences:

1. A strong background in enzyme characterization and enzyme immobilization.
2. Interest in bioelectrochemistry; knowledge in the field is a plus but not required.
3. Hands-on experience in enzyme engineering is an advantage.
4. Motivation for scientific writing and publishing.
5. Excellent command of English, both written and spoken.
6. Strong problem-solving skills.
7. Effective self-management and organizational skills.
8. Ability to collaborate and communicate effectively within an interdisciplinary team.

What You Should Know

*The annual gross salary is EUR 37.500 based on 30 hours/week.

*This corresponds to a monthly net amount of EUR 1.985 (paid 14 times a year).

*Start: 1st of March 2025

Find out more about why acib is the right choice for you:

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And now it’s your turn! Give us an idea of who you are!

*Apply via our application portal: short.acib.at/15-2024

*Application deadline: 31st of January 2025

We are proud to be an equal opportunities employer. We hire on the basis of experience and qualifications, taking into account the requirements of the role. It is particularly important to us that our job offers appeal to all people, regardless of gender, sexual orientation, origin, age, nationality, or religion.

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