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- Aufgaben: Lead the design and characterization of antibodies and proteins in a dynamic lab environment.
- Arbeitgeber: Join Tacalyx, a cutting-edge biopharmaceutical company focused on innovative cancer therapies.
- Mitarbeitervorteile: Enjoy a collaborative work culture and opportunities for professional growth in Berlin.
- Warum dieser Job: Make a real impact in cancer research while working with passionate experts in the field.
- Gewünschte Qualifikationen: Seeking experienced scientists with a strong background in antibody and protein biochemistry.
- Andere Informationen: This role is perfect for self-driven individuals eager to lead and innovate.
Das voraussichtliche Gehalt liegt zwischen 54000 - 84000 € pro Jahr.
Senior Scientist/Group Leader (m/f/d) Antibody and Protein Biochemistry
Tacalyx GmbH is a biopharmaceutical company developing innovative therapeutics to target tumor-associated carbohydrate antigens (TACAs). To strengthen our team in Berlin-Adlershof, we are seeking an experienced, enthusiastic, and self-driven Senior Scientist/Group Leader (m/f/d) Antibody and Protein Biochemistry.
Aufgaben:
- Molecular cloning and expression of recombinant proteins in prokaryotic and mammalian cells
- Organization and conduction of antibody generation projects (e.g., phage display, hybridoma, B-cell cloning, etc.)
- Planning and management of the production of antibodies in different formats (e.g., ADC, bispecific)
- Design and performance of antibody binding assays (e.g., ELISA, Western blot, tailored arrays, SPR)
- Chemical and enzymatic modification of mAbs (e.g., mAb fragmentation, coupling to solid supports or proteins)
- Characterization of antibody preparations (e.g., integrity, activity, stability)
- Preparation of scientific reports and maintenance of the current state of scientific literature
- Collaboration in project teams working on the development of antibodies towards first in human studies
- Management and monitoring of projects with external parties (e.g., CROs, academic groups)
Profil:
- PhD in the field of biological sciences with recent, extensive research laboratory experience
- 2+ years of relevant experience after your PhD in academics or industry
- Hands-on experience with techniques relevant for recombinant protein expression
- Knowledge about antibody production in mammalian cells is expected (experience with ADC or bispecifics is a plus)
- Strong background in antibody technologies and biochemical characterization, knowledge of antibody humanization would be a plus
- Physical experience with different protein chromatography techniques is mandatory (knowledge in HPLC-based method development would be an asset)
- Knowledge of carbohydrate biology would be an asset
- A high level of communication in English and a work permit for Germany (for non-EU applicants) are mandatory
Wir bieten:
- A permanent position with a competitive salary as well as excellent opportunities for professional and personal development
- A diverse, international workforce with a dynamic working environment that fosters creativity, innovation and teamwork
- Annual bonus payment depending on target achievement
- Regular company and team events
- Free “Job ticket” (allows the holder to use local public transport anywhere in Germany)
Important note: Please be advised that a valid work permit for Germany is required for non-EU citizens. Unfortunately, applications without a valid work permit and sufficient German language skills may not be considered.
Karrierestufe
Vollzeit
Tätigkeitsbereich
Forschung, Analyst und IT
Branchen
Biotechnologieforschung
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Senior Scientist/Group Leader (m/f/d) Antibody and Protein Biochemistry Arbeitgeber: TACALYX GmbH
Kontaktperson:
TACALYX GmbH HR Team
StudySmarter Bewerbungstipps 🤫
So bekommst du den Job: Senior Scientist/Group Leader (m/f/d) Antibody and Protein Biochemistry
✨Tip Number 1
Make sure to highlight your experience in antibody and protein biochemistry during the interview. Be prepared to discuss specific projects where you designed or modified proteins, as this will demonstrate your expertise.
✨Tip Number 2
Familiarize yourself with Tacalyx's current research and development projects. Showing that you understand their focus on tumor-associated carbohydrate antigens (TACAs) can set you apart from other candidates.
✨Tip Number 3
Network with professionals in the biopharmaceutical industry, especially those who have experience with antibody development. This can provide you with valuable insights and potentially a referral to Tacalyx.
✨Tip Number 4
Prepare thoughtful questions about the team dynamics and the company's future direction in antibody therapeutics. This shows your genuine interest in the role and helps you assess if it's the right fit for you.
Diese Fähigkeiten machen dich zur top Bewerber*in für die Stelle: Senior Scientist/Group Leader (m/f/d) Antibody and Protein Biochemistry
Tipps für deine Bewerbung 🫡
Understand the Role: Make sure to thoroughly read the job description for the Senior Scientist/Group Leader position at Tacalyx. Understand the key responsibilities and required qualifications, especially focusing on antibody and protein biochemistry.
Highlight Relevant Experience: In your CV and cover letter, emphasize your experience in designing, expressing, characterizing, and chemically modifying antibodies and proteins. Use specific examples to demonstrate your expertise in these areas.
Show Enthusiasm: Tacalyx is looking for enthusiastic candidates. Make sure to convey your passion for biopharmaceuticals and innovative therapeutics in your application materials. A strong motivation letter can help you stand out.
Tailor Your Application: Customize your CV and cover letter to align with the values and goals of Tacalyx. Mention how your skills and experiences can contribute to their mission of developing therapeutics targeting tumor-associated carbohydrate antigens.
Wie du dich auf ein Vorstellungsgespräch bei TACALYX GmbH vorbereitest
✨Show Your Expertise in Antibody and Protein Biochemistry
Be prepared to discuss your previous work with antibodies and proteins in detail. Highlight specific projects where you designed, expressed, or characterized these biomolecules, and be ready to explain the methodologies you used.
✨Demonstrate Your Leadership Skills
As a Group Leader, you'll need to showcase your ability to lead a team. Share examples of how you've successfully managed projects or mentored junior scientists, emphasizing your communication and collaboration skills.
✨Understand Tacalyx's Mission and Products
Research Tacalyx and their focus on tumor-associated carbohydrate antigens (TACAs). Be ready to discuss how your background aligns with their mission and how you can contribute to their innovative therapeutics.
✨Prepare for Technical Questions
Expect technical questions related to antibody design, expression systems, and protein characterization techniques. Brush up on the latest advancements in the field to demonstrate your knowledge and passion for biochemistry.
