Start Date: ASAPLatest Possible Start Date: 01/08/2026Planned Duration of Employment: 12 monthsExtension (for temporary contracts): PossibleMax. Pay Rate: 5+ year 70 chf/h, 8+ years 77 chf/hLocation: BaselWorkload: 100%Home Office: Max. 1 day per WeekThis opportunity lies within analytical development for synthetic molecules, where cutting-edge techniques like high-performance liquid chromatography, gas/ion chromatography, and mass spectrometry are employed to develop efficient and robust analytical methods. The goal is to ensure the release of clinical trial products and their eventual commercial supply through a strong control strategy.The Perfect CandidateThe perfect candidate holds an advanced degree in chemistry or pharmacy and brings a minimum of five years of professional experience in the analytical development of synthetic drug substances. They are a technical expert in liquid chromatography (including HPLC, UHPLC, and advanced detection methods like MS) who can independently drive the development of analytical control packages for intermediates and APIs. As a natural leader and communicator with an excellent command of English, they excel at coaching junior staff, managing external CDMO/CLO activities, and collaborating cross-functionally to deliver seamless project execution. Finally, they possess strong digital acumen, a rigorous approach to statistical data, and proven experience authoring critical regulatory dossiers (such as NDAs) to ensure total data integrityTasks & ResponsibilitiesServe as the Analytical SME/analytical project lead (APL), driving the development of state-of-the-art analytical control packages for synthetic molecules, including direct materials, IPCs, intermediates, and crude APIs.Actively contribute to portfolio delivery by ensuring efficient and effective process development analytics, including the adoption of modern techniques like modelling and simulation.Coaching technicians and junior scientists on project work and serving as a central point of contact for project-related informationSupervise internal laboratory activities and / or testing activities at CLOs/CDMOsCollaborate cross-functionally with key partners in research and early development, Regulatory, and Quality to ensure seamless project execution and alignment.Author, review, and approve critical documents and regulatory dossiers (e.G., QIMPD, NDA) while ensuring compliance with quality standards and data integrity.Act as a Chemistry Project Lead (CPL), leading external testing activities at CDMOs or CLOs, and contributing to the hiring and coaching of new colleagues.Must HavesA Master's or Ph.D. in chemistry, pharmacy, or a related fieldMin. 5 years of professional experience within the analytical development of synthetic molecules drug substancesA robust foundation in liquid chromatography (HPLC and UHPLC) with proficiency in various detection methods, including UV, Mass Spectrometry (MS), fluorescence, and charged aerosol detectionYou possess a solid understanding of analytical chemistry, particularly chromatographic techniques (HPLC, GC), titrations, and various physicochemical methods.You demonstrate excellent collaboration, technical supervision, and project management skills, with a structured and rigorous approachDigital acumen to support digital transformation initiatives;
familiarity with statistical analysis of analytical data is also advantageousExcellent command of the English language. Nice to HavesProficiency in German is considered a plus
