Clinical Sciences Trial Leader (Trial Leadership) – Translational Medicine, Clinical Pharmacology (80-100%)

pSalary Range: CHF93,800.00 - CHF174,200.00 Band Level 4 Job Description Summary Location: Basel, Switzerland LI#-Hybrid We are seeking a Clinical Sciences Trial Leader (CSTL) to join Clinical Sciences Innovation (CSI) – Translational Medicine, in the Clinical Pharmacology team in Basel. This position plays a critical role in the delivery of first-in-human (FIH) and clinical pharmacology studies, representing a major step in the development of new medicines. You will be accountable for the scientific and operational leadership of clinical pharmacology trials, typically conducted in healthy volunteers, ensuring high quality, interpretable data to inform key program decisions. The CSTL role in Clinical Pharmacology is distinct in its strong focus on delivery through others. You will act as the primary bridge between Novartis and the qualified Contract Research Organizations (CROs) conducting clinical pharmacology studies, providing clear direction, oversight and integration from protocol development through to Clinical Study Report (CSR) delivery. This is a highly collaborative, hands‑on role, requiring strong study leadership, excellent communication skills and confidence operating at the interface between internal teams and external partners. This position is based in Basel, with flexibility to work remotely for up to two days a week. Domestic and international travel may be required to support investigator meetings, study team engagement and trial oversight. Work permit support cannot be offered for this role. Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you. /ph3Job Description Key Responsibilities /h3ulliProvide operational leadership for assigned clinical pharmacology studies, including first-in-human and other early phase healthy volunteer trials. /liliAct as independent Clinical Sciences Trial Leader in the Clinical Pharmacology team, accountable for end‑to‑end‑ study delivery from protocol development through to CSR finalization. /liliLead the clinical pharmacology protocol synopsis development process, serving as responsible author in close collaboration with Medical, Pharmacokinetics, Biomarker, Statistics and other cross‑functional‑partners to deliver the protocol synopsis that forms the basis for the selected CRO to develop into a full protocol. /liliServe as the primary Novartis point of contact to the CRO, providing guidance, oversight and challenge to ensure high quality‑study conduct and delivery. /liliLead and coordinate internal cross‑functional study teams, ensuring effective integration of inputs and alignment with CRO activities. /liliOversee study start‑up, conduct and closeout, including review of key deliverables, issue management and risk mitigation. /liliLead the ongoing review of clinical study data, including emerging PK, PD and safety data, supporting timely interpretation and decision making, e.g. for dose escalation decisions. /liliContribute to Clinical Study Reports (CSRs), internal decision documents and program updates, ensuring clarity, scientific rigor and traceability. /liliShare lessons learned and contribute to continuous improvement of clinical pharmacology study delivery. /liliAct as a strong role model within study teams, fostering effective collaboration, accountability and high standards of scientific and operational excellence. /li /ulh3Essential Requirements /h3ulliBachelor’s degree in life sciences or healthcare required; advanced degree (MSc, PhD, PharmD, MD or equivalent) preferred. /liliExperience in clinical pharmacology, early clinical development or clinical trial delivery, ideally within a pharmaceutical environment, for ~2+ years /liliDemonstrated experience contributing to or leading first‑in‑human and/or clinical pharmacology studies, including healthy volunteer trials. /liliStrong experience in protocol development, early phase‑study design and clinical data interpretation, particularly PK/PD and safety data. /liliProven ability to deliver studies through external partners, with experience working closely with CROs and managing outsourced trial conduct. /liliStrong study leadership and coordination skills, with the ability to align diverse stakeholders and drive delivery in a matrix environment. /liliComfortable operating with a high degree of personal ownership and accountability, managing complexity and ambiguity inherent in early phase‑development. /liliA clear growth mindset, with interest in developing own capabilities and contributing positively to team effectiveness and the wider CSI culture. /liliSolid understanding of ICH GCP, regulatory requirements and high‑quality clinical trial conduct, particularly in the context of FIH studies. /li /ulh3Benefits Rewards /h3pExpected Annual Base Salary Range for role: 93,800.00 - 174,200.00 CHF Annual. /pulliThe base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically. /liliIn addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. /liliThe rewards of being part of our team go far beyond base pay and incentives. /liliWe also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. /liliIn addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave. /liliIn addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. /liliLong‑term equity awards granted at group level may also be part of your package. Further details will be provided during the application process. /li /ulpPay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics. Read our brochure to learn more about our global total rewards offering: Note: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process. /ph3Commitment to Diversity and Inclusion / EEO /h3pNovartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. /ph3Accessibility and accommodation /h3pNovartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e‑mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message. /ph3Skills Desired /h3pBudget Management, Clinical Research, Clinical Trial Protocols, Clinical Trials, Coaching, Data Analysis, Data Integrity, Learning Design, Life Science, Risk Monitoring, Trend Analysis Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people’s lives. /ppNovartis is aware of employment scams which make false use of our company name or leader’s names or recruiter’s names to defraud job seekers. Novartis does not make job offers without interview and never asks candidates for money. If you have encountered a job posting or been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond, send money or personal information. Novartis is not responsible for any claims, losses, damages, or expenses resulting from scams. /ppIn the context of China Cross‑Border Data Transfer (CBDT) policy, if you need to apply for a position in China, please go to the local Recruiting System TaleNov . /p #J-18808-Ljbffr