Director, Non-clinical Pharmacology CVR

CSL\’s R&D organization is accelerating innovation to deliver greater impact for patients. With a project-led structure and a focus on collaboration, we’re building a future-ready team that thrives in dynamic biotech ecosystems. Joining CSL now means being part of an agile team committed to developing therapies that make a meaningful difference worldwide.We are seeking a Therapeutic Area (TA) Pharmacology Lead (Cardiovascular & Renal) to drive the design, execution, and interpretation of in vivo pharmacology studies that support drug discovery and development. This role is pivotal in characterising the pharmacological profile of novel therapeutic candidates through internal studies and external collaborations.Main ResponsibilitiesScientific Leadership Define and lead the nonclinical pharmacology strategy for discovery and development programs within the relevant therapeutic area (Cardiovascular and/or Renal)Design and oversee in vivo efficacy, pharmacodynamic (PD), and mechanism-of-action studies in relevant animal modelsGuide the selection and validation of disease models that best represent human pathophysiologyStudy Design & Execution Develop and implement study protocols for pharmacology, target engagement, and biomarker evaluationSelect external collaborators or CROs and collaborate with internal teams, academic collaborators or CROs to ensure high-quality and timely execution of pharmacology studiesAnalyze and interpret complex data sets to inform compound progression and candidate selectionCross-Functional Collaboration Act as Sr. Pharmacology lead on TA teamsWork closely with PK, Toxicology, Translational Science, to integrate pharmacology data into broader development plansParticipate in project teams and TA-teams and provide expert input on pharmacology-related issuesProvide expert input into due diligence for in-licensing or partnership opportunitiesDocumentation & Communication Prepare study reports, presentations, and regulatory documents (e.g., IND, CTA)Present findings to internal stakeholders and external collaborators as neededTeam LeadershipLead and mentor a team of Principal and Sr. scientists, incl. in-vivo lab workFoster a culture of scientific excellence, innovation, and continuous learningQualifications and Experience RequirementsPh.D. in Pharmacology, Physiology, Biomedical Sciences, or a related field10+ years of experience in nonclinical pharmacology within the pharmaceutical or biotech industry or academic background with proven and deep understanding of pharmaceutical developmentStrong expertise in in vivo pharmacology, disease models, and translational science for the relevant TA (Cardiovascular and/or Renal Disease Biology)Familiarity with regulatory expectations for nonclinical pharmacology dataProven ability to manage multiple projects and timelinesStrategic thinker with excellent problem-solving, communication, and interpersonal skillsExperience across multiple therapeutic areas and modalities is highly desirableExtensive knowledge in one of Cardiovascular or Renal Biology is essential; both would be viewed highly favorablyAre you interested? We are looking forward to receiving your online application.Our BenefitsWe encourage you to make your well-being a priority. It’s important and so are you. Learn more about how we care at CSL.About CSL BehringCSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.We want CSL to reflect the world around usAt CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. Learn more Inclusion and Belonging | CSL.Do work that matters at CSL Behring!