Principal Investigator (Lübeck) in Berlin

Key Responsibilities

• Act as Principal Investigator across Phase I-IV clinical trials, with a particular focus on vaccine studies.
• Provide medical leadership and oversight throughout the full clinical trial lifecycle.
• Ensure participant safety, welfare, and protocol compliance at all times.
• Conduct and supervise screening, enrolment, eligibility assessments, and study visits.
• Review adverse events, serious adverse events, and safety data.
• Ensure studies are conducted in accordance with ICH-GCP, local regulations, and sponsor requirements.
• Maintain oversight of source documentation, data quality, and protocol adherence.
• Collaborate closely with Clinical Research Coordinators, Study Nurses, Sub-Investigators, and Clinical Operations teams.
• Participate in sponsor meetings, site visits, audits, and regulatory inspections.
• Support patient recruitment and retention strategies.
• Contribute to site growth initiatives and evaluation of future research opportunities.
• Mentor junior investigators and clinical research staff where appropriate.

Requirements

Essential

• Medical Doctor (MD) qualification.
• Full medical registration/licensure in Germany or eligibility to practice.
• Previous experience in clinical research as a Principal Investigator, Sub-Investigator, or Research Physician.
• Strong understanding of ICH-GCP guidelines and clinical trial regulations.
• Ability to make sound medical decisions in a research environment.
• Excellent communication and stakeholder-management skills.
• Fluent English language skills.

Desirable

• Experience within vaccine, infectious disease, immunology, public health, or preventative medicine studies.
• Prior responsibility for participant safety review and adverse event assessment.
• Experience interacting with sponsors, CROs, ethics committees, and regulatory authorities.
• GCP certification.
• German language skills.

What Is Offered

• Salary up to €135,000 per annum.
• Opportunity to work on a high-profile vaccine programme with significant public health impact.
• Established clinical research infrastructure and dedicated site support.
• Exposure to cutting-edge vaccine development and international sponsors.
• Strong long-term career progression opportunities within clinical research leadership.
• Collaborative and scientifically driven working environment.

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