Finde einen Job 
Finde eine Ausbildung 
Top Arbeitgeber 
Top Universitäten 
Für Unternehmen Auf einen Blick
- Aufgaben: Dive into groundbreaking research on ageing and epigenetics in frog embryos.
- Arbeitgeber: Join the International PhD Programme (IPP) Mainz, a hub for innovative life sciences research.
- Mitarbeitervorteile: Enjoy fully funded positions, advanced training, and access to state-of-the-art facilities.
- Warum dieser Job: Collaborate with diverse scientists and push the boundaries of biological research in a vibrant community.
- Gewünschte Qualifikationen: Master's degree or equivalent, strong background in Molecular or Developmental Biology, and good English skills.
- Andere Informationen: Apply by April 3, 2025, for a chance to start your PhD on August 1, 2025.
Das voraussichtliche Gehalt liegt zwischen 36000 - 60000 € pro Jahr.
Organisation/Company: International PhD Programme (IPP) Mainz
Department: Institute of Molecular Biology
Research Field: Biological sciences » Biology
Researcher Profile: First Stage Researcher (R1)
Positions: PhD Positions
Country: Germany
Application Deadline: 3 Apr 2025 – 12:00 (Europe/Berlin)
Type of Contract: Temporary
Job Status: Full-time
Offer Starting Date: 1 Aug 2025
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
Offer Description
Thinking of doing your PhD in the Life Sciences? The International PhD Programme (IPP) Mainz is offering talented, young scientists the chance to work on cutting edge research projects within the open call on “Molecular Mechanisms in Genome Stability & Gene Regulation” . As an IPP PhD student, you will join a community of exceptional scientists working on diverse topics ranging from how organisms age or how our DNA is repaired, to how epigenetics regulates cellular identity or neural memory.
Activities and Responsibilities
The research group of Christof Niehrs offers the following PhD project:
Ageing is commonly believed to start in adulthood. However, there is increasing evidence that organismic ageing begins already during embryonic development. For example, analyses of Down syndrome show pronounced acceleration of ageing markers already in fetal stages, similar to adult tissues. This indicates that mechanisms of ageing may be productively studied during embryogenesis.
You will study the role of progeria genes, which lead to premature ageing, in frog (Xenopus) embryos. We have recently shown that the epigenetic clock is applicable to frogs as it is in humans (Zoller et al., 2023). Using epigenetic clock analysis, you will characterize cellular ageing and senescence in developing frog tissues using immunofluorescence microscopy. You will analyze epigenetic profiles in premature ageing embryos by Next Generation Sequencing to understand the molecular network involved in these phenotypes. You will learn to analyze these Big Data by bioinformatic analysis. You will work in a team of developmental biologists and bioinformaticians. The successful candidate will have a strong background in Molecular or Developmental Biology to study ageing-related phenotypes in embryos. You will apply techniques including embryo culture , microinjection , RNA in situ hybridisation , confocal microscopy , Next Generation Sequencing and bioinformatics data analysis .
If you are interested in this project, please select Niehrs (Ageing) as your group preference in the IPP application platform.
Qualification Profile:
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
- Master or equivalent
- Interactive personality & good command of English
- 2 letters of reference
We Offer:
- Exciting, interdisciplinary projects in a lively international environment, with English as our working language
- Advanced training in scientific techniques and professional skills
- Access to our state-of-the-art Core Facilities and their technical expertise
- Fully funded positions with financing until the completion of your thesis
- A lively community of more than 200 PhD students from 44 different countries
For more details on the projects offered and how to apply via our online form, please visit .
The deadline for applications is 3 April 2025. Interviews will take place at IMB in Mainz on 23 & 24 June 2025.
Starting date: 1 August 2025 – 1 January 2026
#J-18808-Ljbffr
PhD position: Ageing, Embryos & Epigenetics (m/f/d) Arbeitgeber: EURAXESS
Kontaktperson:
EURAXESS HR Team
StudySmarter Bewerbungstipps 🤫
So bekommst du den Job: PhD position: Ageing, Embryos & Epigenetics (m/f/d)
✨Tip Number 1
Familiarize yourself with the latest research in molecular biology, particularly in the areas of ageing and epigenetics. This will not only help you understand the project better but also allow you to engage in meaningful discussions during the interview.
✨Tip Number 2
Connect with current or former PhD students from the IPP Mainz to gain insights into their experiences. They can provide valuable information about the application process and what to expect during your PhD journey.
✨Tip Number 3
Highlight any relevant laboratory techniques you have experience with, such as Next Generation Sequencing or immunofluorescence microscopy, in your conversations. This will demonstrate your readiness for the practical aspects of the research.
✨Tip Number 4
Make sure to express your enthusiasm for interdisciplinary collaboration. The IPP values teamwork across different scientific fields, so showing that you are open to working with bioinformaticians and developmental biologists will set you apart.
Diese Fähigkeiten machen dich zur top Bewerber*in für die Stelle: PhD position: Ageing, Embryos & Epigenetics (m/f/d)
Tipps für deine Bewerbung 🫡
Understand the Research Focus: Familiarize yourself with the specific research project on ageing and epigenetics. Highlight your interest in these areas and how your background aligns with the goals of the research group led by Christof Niehrs.
Tailor Your CV: Ensure your CV reflects relevant experience in Molecular or Developmental Biology. Include any specific techniques you are proficient in, such as RNA in situ hybridization or Next Generation Sequencing, to demonstrate your suitability for the position.
Craft a Strong Motivation Letter: Write a compelling motivation letter that outlines your passion for the research topic, your academic achievements, and your career aspirations. Make sure to express why you want to join the IPP and how you can contribute to the team.
Gather References: Secure two strong letters of reference from individuals who can speak to your research abilities and character. Ensure they understand the focus of the PhD position so they can tailor their recommendations accordingly.
Wie du dich auf ein Vorstellungsgespräch bei EURAXESS vorbereitest
✨Know Your Research
Make sure you are well-versed in the latest research related to ageing, epigenetics, and developmental biology. Familiarize yourself with key studies, especially those relevant to the project you are applying for, as this will demonstrate your genuine interest and knowledge.
✨Prepare for Technical Questions
Expect questions about specific techniques mentioned in the job description, such as Next Generation Sequencing, immunofluorescence microscopy, and bioinformatics. Be ready to discuss your experience with these methods and how they relate to the research project.
✨Show Your Collaborative Spirit
Since the position involves working in a team of developmental biologists and bioinformaticians, highlight your ability to collaborate effectively. Share examples from your past experiences where teamwork led to successful outcomes.
✨Ask Insightful Questions
Prepare thoughtful questions about the research group, ongoing projects, and the IPP community. This shows your enthusiasm for the position and helps you assess if the environment aligns with your career goals.
