pFor our Client, a leading pharmaceutical company based in Basel, we are looking for a motivated NGS Scientist- /p pSingle-cell and spatial omics technologies are transforming biomedical research by enabling deep characterization of complex biological systems at unprecedented resolution. These technologies provide critical insights into cellular heterogeneity, disease mechanisms, therapeutic responses, and translational biology. /p pWe are seeking a highly motivated Scientist / Associate Scientist to join a cutting-edge genomics platform team focused on single-cell sequencing, spatial transcriptomics, and next-generation sequencing (NGS) applications. The successful candidate will work at the interface of molecular biology, genomics, and translational research, supporting the development and implementation of innovative omics technologies that accelerate scientific discovery and therapeutic innovation. /p h3Key Responsibilities /h3 ul liDevelop, optimize, and implement advanced NGS-based workflows with a focus on: /li liSingle-cell RNA sequencing (scRNA-seq) /li liSpatial transcriptomics /li liMulti-omics and multimodal profiling approaches /li liIndependently perform molecular biology experiments and troubleshoot complex workflows. /li liExecute sample processing, nucleic acid extraction, PCR/qPCR, library preparation, sequencing, and quality control activities. /li liGenerate, analyze, and document experimental results with a high level of scientific rigor. /li liWork with challenging sample types including FFPE tissues, primary samples, and low-input materials. /li liCollaborate closely with bioinformatics and cross-functional research teams to interpret sequencing datasets and derive biological insights. /li liEnsure generation of high-quality, FAIR-compliant data. /li liPresent scientific findings, protocols, and recommendations to internal stakeholders. /li liContribute to continuous innovation and enhancement of platform capabilities. /li /ul h3Required Qualifications /h3 ul liMaster's degree in Molecular Biology, Biotechnology, Biochemistry, Life Sciences, Genomics, or a related discipline. /li li1-3 years of industry or relevant research experience in genomics or molecular biology. /li liHands-on experience with Next-Generation Sequencing (NGS) workflows. /li liStrong expertise in: /li liDNA/RNA extraction /li liPCR and qPCR /li liNGS library preparation /li liMolecular biology laboratory techniques /li liExperience handling clinical or challenging biological samples such as FFPE tissue, tumor specimens, or low-input samples. /li liProven ability to independently design, execute, analyze, and troubleshoot experiments. /li liStrong communication skills and ability to collaborate effectively within multidisciplinary teams. /li liFluent English. /li /ul h3Preferred Qualifications /h3 ul liHands-on experience with single-cell sequencing platforms (e.g. 10x Genomics Chromium). /li liExperience with spatial transcriptomics and spatial biology technologies (e.g. Visium, Xenium, CosMx, RNAscope). /li liKnowledge of transcriptomics, genomics, and multi-omics approaches. /li liExperience with assay development, method optimization, and technology implementation. /li liFamiliarity with basic bioinformatics analyses and interpretation of sequencing datasets. /li liExperience in a pharmaceutical, biotechnology, or translational research environment. /li /ul h3What We're Looking For /h3 pWe are particularly interested in candidates who combine strong wet-lab genomics expertise with a passion for emerging technologies such as single-cell sequencing and spatial biology. Successful candidates are curious, innovative, collaborative, and excited about applying cutting-edge omics technologies to advance translational research and therapeutic discovery. /p #J-18808-Ljbffr
NGS Scientist (single-cell and spaital Omics) Arbeitgeber: Gi Life Sciences Basel
Hoffmann-La Roche in Basel bietet Ihnen die Möglichkeit, in einem hochmodernen biotechnologischen Produktionsumfeld zu arbeiten, das sich durch eine dynamische und teamorientierte Kultur auszeichnet. Als Teil des Manufacturing Lab Teams tragen Sie aktiv zur Herstellung innovativer Medikamente bei und profitieren von umfangreichen Weiterbildungsmöglichkeiten sowie einer klaren Karriereentwicklung. Der Standort Basel ermöglicht zudem eine hervorragende Work-Life-Balance und ein inspirierendes Arbeitsumfeld in einer der lebenswertesten Städte der Schweiz.