Principal DMPK Scientist, Preclinical Biology & Pharmacology

h3Principal Scientist, Preclinical Biology Pharmacology - DMPK /h3 h3Location: Switzerland | Relocation support available /h3 pWe are supporting a global RD innovative FMCG organisation in the appointment of a bPrincipal Scientist, Preclinical Biology Pharmacology /b to perform experimental pre-clinical DMPK. /p pYou should have previous bhands-on laboratory pre-clinical DMPK experience, you can independently design DMPK studies, lead their execution internally or through CROs, interpret the results and use them to make compound-development decisions. /b /p pThis is a senior individual-contributor position for an experienced scientist who has progressed from hands-on research into leading multidisciplinary DMPK/ADME programmes and guiding the scientific strategy required to progress novel compounds. /p h3The role /h3 pYou will develop the DMPK/ADME strategy and lead its implementation and execution across novel-compound programmes. /p pThe research may involve bin vitro, ex vivo and in vivo approaches /b, with the Principal Scientist responsible for bringing together evidence from different scientific disciplines to guide programme decisions. /p pYou do not need to personally perform every type of study. You should, however, understand how the different evidence streams fit together and be able to provide scientific direction to specialists contributing to the programme. /p h3You will: /h3 ul liDevelop and lead DMPK strategies for novel compounds. /li liLead the implementation and execution of DMPK programmes from a scientific and operational perspective. /li liDetermine the studies and evidence required to support programme progression. /li liLead multidisciplinary project teams without direct line-management responsibility. /li liUse bPK, DMPK, ADME information /bto inform development decisions. /li liCritically evaluate scientific data, study designs and proposed development strategies. /li liWork closely with Project Management, Clinical, Computational Biology and other scientific specialists within a matrix RD environment. /li liProvide scientific guidance while drawing on expertise from specialists across different disciplines. /li liTranslate complex science into clear recommendations for senior stakeholders. /li liPresent scientific programmes, strategies and recommendations to senior leadership and governance groups. /li liWork with internal scientists and external research partners where appropriate. /li /ul h3What we're looking for /h3 ul liPhD in Pharmacology or Biological Sciences /li liMinimum of 5 years of experience post-PhD in Drug Metabolism and Pharmacokinetics with demonstrated experience of advancing research programs to key internal decision points and evidence-based innovations/product outcomes. /li liDemonstrated expertise in health areas such as neuroscience, pulmonary health, cardiovascular health, oral health. /li liStrong business acumen gained through industry leadership experience involving scientific and operational leadership /li liSound scientific and operational leadership, critical thinking, strategic mindset, result-focus and analytical skills/problem-solving/data driven decision-making skills. /li liCreativity / innovation mindset. /li liStrong engagement, influencing and communication skills. /li liFluency in both written and spoken English. /li liHolding an EU/EFTA/Switzerland passport or having a valid legal right to work in Switzerland, and being able to relocate. /li /ul h3Particularly valuable experience /h3 pExperience applying pharmacology across bmore than one relevant health territory /b would be particularly valuable, especially across neuroscience, cardiovascular/cardiometabolic, pulmonary/respiratory or oral health. /p pWe are interested in scientists who have worked with bsmall molecules and/or other relevant bioactive compounds /b. The role is not primarily focused on monoclonal antibodies, gene therapies or other advanced therapeutic modalities. /p h3What's in it for you? /h3 pJoin a blarge, well-funded global organisation /b with a strong focus on science, innovation and future product development. /p pYou will have the opportunity to lead scientifically complex programmes, work across multiple health territories and scientific disciplines, and influence important development decisions while remaining closely connected to the science. /p pThe position offers a bcompetitive salary and benefits package /b, along with brelocation support to Switzerland /b. /p pbIf you’re an experienced DMPK scientist who enjoys bringing together different areas of science to guide novel compounds through development, we’d love to hear from you. /b /p h3Before applying: /h3 pPlease review the must-have requirements carefully and answer the screening questions accurately. These reflect specific criteria agreed with the hiring team and will be verified against your experience before progression. /p #J-18808-Ljbffr