Innovation Postdoctoral Fellow in Biologics

Innovation Postdoctoral Fellow in Biologics

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Salary Range CHF 0.00 - CHF 0.00
Job Description Summary We are excited to invite applications for the Novartis Biomedical Research Postdoctoral Fellowship Program, a unique training opportunity designed for exceptional early‑career scientists eager to tackle some of the most challenging problems in biomedical research and drug discovery.
Location: Basel, Switzerland
Duration: 3 years
Program start date: October 1, 2026
Application deadline: July 15, 2026 EOB
Job Description As a Postdoctoral Research Fellow, you will join Biologics Research Center (BRC) in Basel and pursue an innovative research project at the forefront of biomedical science and drug discovery. You will work alongside leading scientists in a highly collaborative, multidisciplinary environment while gaining exposure to the broader ecosystem that translates scientific discovery into medicines.
Our fellows are empowered to ask bold scientific questions, apply cutting‑edge technologies, and develop approaches that have the potential to transform patient care.
Research Opportunity You will join the Cell Line Screening & Development unit, which develops manufacturing CHO cell lines for Novartis’ increasingly complex biotherapeutics pipeline. Working at the interface of research and technical development, you will gain exposure to the early biologics discovery and development process, from molecule design and developability assessment to technical development. Your project will focus on advancing a next‑generation CHO platform by evaluating transposon‑based gene integration systems. In close collaboration with partners in BRC and Technical Research and Development (TRD), you will contribute to an end‑to‑end production platform that supports early research through clinical and commercial supply.
To support this work, you will establish high‑throughput capabilities for future artificial intelligence/machine learning approaches, from plasmid library design to screening systems with tailored molecule design, and identify multi‑specific antibody producers with optimal productivity and quality. You will also apply state‑of‑the‑art genetic characterization to the resulting CHO pools and clones and help generate AI‑ready data.
Your work will help advance cell line development technologies and may enable faster, more reliable generation of production cell lines for next‑generation biologics.
Why Join the Program? The Novartis Biomedical Research Postdoctoral Fellowship Program is designed to develop the next generation of scientific leaders and power the future of medicine through rigorous research, and immersive learning experiences, including the implementation of AI tools in biomedical research.
Postdoctoral Research Fellows benefit from:
Guidance from accomplished scientific leaders and subject matter experts
Access to advanced technologies, platforms, and research capabilities
Collaboration across disciplines and organizational boundaries
A global and diverse community of postdoctoral fellows
Dedicated programming designed to help fellows thrive throughout their careers.
Personalized experiential learning opportunities through a Postdoc Practicum that empower fellows to explore new scientific domains, build cross‑functional expertise, and expand their impact beyond their primary research project.
Opportunities to present research, publish in leading journals, and build an international scientific network
Reimagining Medicine Together At Novartis, our purpose is to reimagine medicine to improve and extend people’s lives. Through this program, you will grow as a scientist and future leader while contributing to discoveries that may ultimately benefit patients worldwide.
Start Date October 2026
Key Responsibilities
Design and perform high‑throughput molecular cloning of plasmids and plasmid libraries
Establish and optimize transposon‑based workflows for stable gene integration and generation of engineered CHO cell pools
Culture, maintain, transfect, and characterize mammalian cells, with a primary focus on CHO suspension cell system
Design and execute experiments to compare transposon system performance, including integration efficiency, pool diversity, expression levels, productivity, and stability
Develop, optimize, and troubleshoot protocols for cell pool generation, selection, and expansion
Apply molecular biology and analytical methods to characterize engineered cell pools, including assessment of transgene integrity, expression, copy number, and productivity where appropriate
Collaborate closely with scientists across Biologics Research Center, Technical Research & Development, and automation/data science functions
Analyze, interpret, and clearly communicate experimental results through presentations, reports, and scientific discussions
Document technical developments and contribute to invention disclosures and patent filings
Essential Requirements
PhD (or equivalent doctoral degree) in a relevant scientific discipline completed prior to the fellowship start date. The program is intended for scientists immediately following their PhD training (PhD conferred in 2026 only).
Demonstrated record of scientific achievement (publications, presentations, patents, or equivalent)
Strong commitment to learning, innovation, and professional development
Strong hands‑on experience with mammalian suspension cell culture, transfection, selection, expansion, and cell banking
Solid background in molecular biology techniques relevant to cell engineering, such as plasmid design, cloning, DNA/RNA analysis, and transgene expression assessment
Demonstrated ability to independently design, execute, troubleshoot, and interpret complex biological experiments
Experience generating AI‑ready datasets, including structured metadata capture and basic computational analysis.
Strong team player with excellent communication skills and the ability to work effectively in a collaborative, multidisciplinary environment
High scientific curiosity, rigor, and motivation to develop innovative technologies for biologics research and cell line development
Desirable Requirements
Experience with CHO cell line development, stable pool generation, recombinant protein expression, or high‑throughput plasmid design and cell engineering workflows or upstream process development
Experience working with large omics datasets and libraries, with familiarity in programming languages such as R or Python.
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Innovation Postdoctoral Fellow in Biologics Arbeitgeber: Healthcare Businesswomen’s Association

Als Arbeitgeber bieten wir Ihnen die Möglichkeit, in einem dynamischen und innovativen Umfeld zu arbeiten, das auf Zusammenarbeit und Kreativität setzt. Unsere Unternehmenskultur fördert kontinuierliches Lernen und persönliche Entwicklung, während wir gleichzeitig attraktive Vergütungen und umfassende Sozialleistungen anbieten. In dieser Rolle als Associate Director in der Schweiz profitieren Sie von einem inspirierenden Arbeitsumfeld, das Ihre beruflichen Ambitionen unterstützt und Ihnen die Chance gibt, an bedeutenden Projekten mitzuarbeiten.

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Healthcare Businesswomen’s Association Recruiting-Team