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- Aufgaben: Join our team to develop cutting-edge single-cell RNA-seq technologies and study gene expression dynamics.
- Arbeitgeber: Helmholtz Munich is a leader in biomedical research, improving health through innovative solutions.
- Mitarbeitervorteile: Enjoy 30 days of annual leave, flexible workdays, and support for relocation and integration.
- Warum dieser Job: Be part of an interdisciplinary team making impactful discoveries in stem cell biology and genomics.
- Gewünschte Qualifikationen: PhD in Systems Biology or related field; strong publication record and experience in computational and experimental work.
- Andere Informationen: We value diversity and inclusion, welcoming applicants from all backgrounds.
Das voraussichtliche Gehalt liegt zwischen 42000 - 60000 € pro Jahr.
Postdoc (f/m/x) in time-resolved single-cell omics and stem cell biology
102622
Full time
39 hrs./week
Neuherberg near Munich
We are Helmholtz Munich. We discover breakthrough solutions for better health in a rapidly changing world.
We improve people’s quality of life through excellent research. Why not join us and make a difference?
TheHelmholtz Pioneer Campus (HPC) founded and funded by Helmholtz Munich stands for the intelligent fusion of biomedical sciences, engineering and digitization. At HPC, top scientific talents from across the globe work together on the development of novel solutions that make a difference in the prevention, diagnosis and treatment of diseases.
We are looking for a postdoc (f/m/x) to join our team to develop new time-resolved single-cell RNA-seq technologies and study the interplay between gene oscillations and cellular decision making in stress and during differentiation.
At the Battich lab we are an interdisciplinary team that loves to develop cutting-edge quantitative methods for single-cell genomics and combine them with cellular phenotyping using high-content confocal microscopy. We design data-driven approaches and build quantitative predictive models and use state-of-the-art machine-learning to gain insights into the cellular processes we study.
Your tasks
- Design and characterize new single-cell sequencing approaches to study gene expression dynamics and oscillations, based on metabolic labelling of RNA.
- Characterize the genome wide dynamics in expression in different differentiation systems such as models of embryo segmentation and/or neural differentiation.
- Work in a team to build quantitative models of gene expression dynamics based on interpretable AI.
- Elucidate mechanisms of how transcriptional dynamics propagate through the genome via gene regulatory networks.
- Analyse and integrate diverse datasets (e.g., single-cell genomics, proteomics and high-throughput fluorescent microscopy).
- Use CRISPR-Cas9 perturbation of chromatin regulators to investigate their effects on single-cell transcriptional dynamics.
Your profile
- PhD in Systems Biology, Genetics, Molecular & Cell Biology or a related quantitative biology discipline.
- Good publication record with evidence of independence (at least one first-author publication in an international journal).
- Interest and experience combining computational and experimental work, including demonstrated competency in scientific programming.
- Experience performing next-generation sequencing experiments, and/or CRISPR-Cas9 technology.
- Fluent in written and spoken English.
Desirable qualifications
- Experience with experimental work using stem cells or organoid model systems.
Benefits
- Career Development: Postdoc program, scientific training & career center with tailored offers
- Recreation: 30 days annual leave, flexi days, plus public holidays
- International Staff Service: Support with the relocation and integration process in Germany
- Health Promotion: Sports, company doctor, mental health initiatives
Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.
Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality.
The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees.
If you fulfil all the requirements, you may be eligible for a salary grade of up to E 13. Social benefits are based on the Collective Wage Agreement for Public-Sector Employees (TVöD). The position has an (initial) fixed term of 2 years but may be extended under certain circumstances.
We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree.Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.
Interested in applying?
If you have any questions, feel free to contact Nicolas Battich, , who will be happy to help.
Your application should include
- CV
- Cover letter
- Degrees/Diplomas/Certificates
- Contact details for at least two referees
Helmholtz Pioneer Campus @Helmholtz Munich
Why join us?
Helmholtz Munich
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz Pioneer Campus
Ingolstädter Landstraße 1
85764 Oberschleißheim
#J-18808-Ljbffr
Postdoc (f/m/x) in time-resolved single-cell omics and stem cell biology Arbeitgeber: Helmholtz Zentrum München
Kontaktperson:
Helmholtz Zentrum München HR Team
StudySmarter Bewerbungstipps 🤫
So bekommst du den Job: Postdoc (f/m/x) in time-resolved single-cell omics and stem cell biology
✨Tip Number 1
Make sure to highlight your experience with next-generation sequencing and CRISPR-Cas9 technology during the interview. Be prepared to discuss specific projects where you applied these techniques, as this will demonstrate your hands-on expertise.
✨Tip Number 2
Familiarize yourself with the latest advancements in single-cell RNA-seq technologies. Being able to discuss recent papers or breakthroughs in this area can show your passion and commitment to the field.
✨Tip Number 3
Since the role involves interdisciplinary collaboration, be ready to share examples of how you've successfully worked in teams that combine computational and experimental approaches. This will highlight your adaptability and teamwork skills.
✨Tip Number 4
Prepare to discuss your publication record in detail, especially your first-author publications. This is a key indicator of your independence and research capabilities, which are crucial for a postdoc position.
Diese Fähigkeiten machen dich zur top Bewerber*in für die Stelle: Postdoc (f/m/x) in time-resolved single-cell omics and stem cell biology
Tipps für deine Bewerbung 🫡
Understand the Role: Make sure to thoroughly read the job description and understand the specific requirements and responsibilities of the postdoc position. Tailor your application to highlight how your skills and experiences align with these expectations.
Craft a Strong Cover Letter: In your cover letter, clearly express your motivation for applying to Helmholtz Munich and the Battich lab. Discuss your relevant research experience, particularly in single-cell omics and stem cell biology, and how it relates to the projects mentioned in the job description.
Highlight Your Publications: Since a good publication record is essential, make sure to list your publications prominently in your CV. If you have a first-author publication, emphasize it as evidence of your independence in research.
Prepare References: Include contact details for at least two referees who can speak to your qualifications and research capabilities. Choose individuals who are familiar with your work and can provide a strong endorsement of your skills and potential.
Wie du dich auf ein Vorstellungsgespräch bei Helmholtz Zentrum München vorbereitest
✨Showcase Your Research Experience
Be prepared to discuss your previous research projects in detail, especially those related to single-cell genomics and stem cell biology. Highlight any first-author publications and how they demonstrate your independence and expertise in the field.
✨Demonstrate Interdisciplinary Skills
Since the role involves combining computational and experimental work, be ready to explain how you have successfully integrated these areas in your past projects. Discuss any experience with scientific programming and next-generation sequencing experiments.
✨Prepare for Technical Questions
Expect questions about specific techniques mentioned in the job description, such as CRISPR-Cas9 technology and high-content confocal microscopy. Brush up on these topics and be ready to discuss your hands-on experience with them.
✨Express Your Interest in Team Collaboration
The Battich lab values teamwork, so convey your enthusiasm for working in an interdisciplinary team. Share examples of how you have collaborated with others in your research and how you can contribute to building quantitative models of gene expression dynamics.
