The University of Applied Sciences and Arts Western Switzerland Valais (HES-SO Valais-Wallis) has over 2,800 students. Through research and innovation, it contributes to economic and social development and the creation of jobs. The new Energypolis campus, home to the School of Engineering, EPFL and modern start-ups, is an ecosystem for research. Why not come join us?The School of Engineering at the Energypolis campus invites applications for the following position within the Institute of Systems Engineering:Postdoctoral Researcher in AI/ML-driven LC-MS (80%)The Mass Spectrometry and Proteomics group at HES-SO Valais-Wallis is seeking a highly motivated and skilled Postdoctoral Researcher with expertise in liquid chromatography high-resolution mass spectrometry (LC-HRMS), proteomics and biotherapeutic analysis. The successful candidate will combine hands-on Orbitrap-based analysis with active participation in the development of AI/ML-assisted data processing, working in a multidisciplinary team of scientists, engineers and industry partners.Responsibilities:- Operate and maintain the LC-Orbitrap system, including setup and routine troubleshooting.- Develop and execute protocols for intact-mass and peptide-mapping analysis of monoclonal antibodies and biopharmaceuticals.- Perform data acquisition, processing, and reporting, including method development (MAM) and validation.- Analyze host cell protein (HCP) data.- Collaborate with software engineers to design, test and implement AI/ML algorithms for LC-HRMS data analysis.- Collaborate with industry partners to translate research methods into industrial workflows.- Contribute to manuscripts, project reports and scientific presentations.Selection criteria:- PhD in Analytical Chemistry, Biochemistry or a related field.- Proven hands-on experience with LC-HRMS, specifically Orbitrap mass spectrometers.- Experience with protein/biopharmaceutical sample preparation and LC-MS analysis.- Working proficiency in at least one scripting language (R, Python or similar) for data handling and analysis.- Assets include: experience with antibody characterization; familiarity with MAM and HCP analysis; experience applying AI/ML to analytical chemistry; experience with nano/micro LC and microfluidics.- Proficiency in English (spoken and written) is required; French and German language skills are a plus.We offer:- Applied research addressing real-world challenges in AI/ML and proteomics.- Collaboration with expert scientists, engineers and industry partners to develop mass spectrometry methods and tools.- Excellent teaching and research facilities in a modern analytical chemistry environment, with the opportunity to develop teaching and student mentoring skills.- Position based in Sion, a picturesque town in the heart of the Alps and the sunny capital of Valais.Employment level: 80%Place of work: SionStarting date: November 2024 or upon agreementContract duration: 2 yearsFor further information please contact the professor in charge. Please submit your complete application documents (CV, cover letter, diplomas and certificates) by 21 August 2024 by clicking on the Apply button. Only online applications will be considered. jidb43b3e7aen jit0730aen jpiy26aen
Postdoctoral Researcher in Artificial Intelligence and Machine Learning for Biopharmaceutical Charac Arbeitgeber: HES-SO Valais-Wallis
Die Haute Ecole d’Ingénierie der HES-SO Valais-Wallis bietet eine inspirierende Arbeitsumgebung, die auf Teamarbeit und Innovation setzt. Mit einem klaren Fokus auf die Entwicklung von Fachkräften im Bereich der Sicherheit und des Bevölkerungsschutzes am Campus Energypolis, fördert das Unternehmen kontinuierliches Lernen und persönliche Weiterentwicklung. Die Möglichkeit, aktiv an der Prävention von Naturgefahren mitzuwirken und die Gemeinschaft zu unterstützen, macht diese Position besonders bedeutungsvoll und bereichernd.
