We are seeking an experienced scientist to lead the development of a novel retrotransposon-based platform for in vivo CAR-T/CAR-NK therapies. This role combines scientific leadership with hands-on research, managing a small team while advancing a first-in-class gene integration technology.Key ResponsibilitiesLead strategy and execution of retrotransposon-based gene integration approaches for in vivo cell engineering.Design and optimize RNA templates, integration systems, and delivery strategies.Partner closely with LNP/mRNA delivery teams to enable efficient in vivo transduction.Mentor and manage a team of scientists while maintaining laboratory involvement.Collaborate across research, development, and CMC functions to advance programs toward the clinic.Present data, contribute to IP generation, and drive scientific innovation.QualificationsPhD in Molecular Biology, Genetics, Biochemistry, or related field with 8+ years of relevant experience.Expertise in retrotransposons, retrons, reverse transcriptase-based systems, or related gene integration technologies.Experience with mRNA and/or LNP delivery platforms.Strong leadership, mentoring, and research team management skills.Background in molecular engineering, cell-based assays, and translational research.PreferredExperience in CAR-T/CAR-NK or cell therapy.Knowledge of non-viral gene editing/integration technologies.Familiarity with IND-enabling studies and early development.Experience engaging with senior leadership and external stakeholders.
Principal Scientist in Lausanne Arbeitgeber: IGI
IGI in Lausanne bietet eine inspirierende Arbeitsumgebung, die Innovation und Zusammenarbeit fördert. Als Arbeitgeber legen wir großen Wert auf die berufliche Weiterentwicklung unserer Mitarbeiter und bieten zahlreiche Möglichkeiten zur Weiterbildung und Karriereförderung. Unsere moderne Ausstattung und der interdisziplinäre Austausch machen uns zu einem attraktiven Arbeitsplatz für Wissenschaftler, die an der Spitze der Antikörperforschung stehen möchten.
