Senior COA Scientist, Scoring & Interpretation

Senior COA Scientist, Scoring & Interpretation

Frankfurt am Main Vollzeit Kein Homeoffice möglich
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  • Provide scientific leadership across COA evaluation and implementation, applying expertise in measure development, instrument documentation, scoring methodology, and interpretation to ensure outputs are scientifically robust and fit for clinical research use.

  • Contribute to high-quality COA science across the organisation by supporting methodological best practices, reviewing scientific deliverables, collaborating with cross-functional teams, and strengthening scalable processes for both instrument-related and scoring-related work.

  • Interpret scoring manuals, instrument documentation, publications, and related source materials to define scientifically valid, implementation‑ready scoring requirements, including score structures, derivations, recoding, transformations, weighting, and conditional logic.

  • Define and document missing‑data handling rules, minimum completion thresholds, suppression logic, and other algorithm requirements where source guidance is incomplete, ambiguous, or complex.

  • Assess and document interpretation guidance associated with COA scores, including severity bands, score meaning, benchmarks, and other clinically relevant interpretation outputs where supported.

  • Identify, evaluate, and resolve ambiguities in scoring methodology, escalating appropriately when scientific judgement, author clarification, or senior SME input is required.

  • Partner with statisticians, programmers, product, and engineering teams to translate scientific requirements into validated scoring implementations.

  • Investigate discrepancies, implausible outputs, and scoring‑related issues to determine root cause and support robust resolution.

  • Serve as the scientific point of contact for internal queries related to scoring logic, interpretation, algorithm complexity, and implementation feasibility.

  • Contribute to standard templates, SOPs, review checklists, and reusable scientific assets that improve the quality, consistency, and scalability of scoring operations.


Requirements



  • Advanced degree (PhD, MSc, MPH, PharmD, psychology, outcomes research, public health, psychometrics, epidemiology, health sciences, or related discipline).

  • Minimum 7 years of relevant experience in COA science, outcomes research, psychometrics, patient‑centered research, or closely related scientific roles within pharma, CRO, healthcare research, or instrument development.

  • Experience with instrument development, validation, psychometric evidence, or interpretation / meaningful‑change work.

  • Deep familiarity with COA concepts, including domains, scoring structures, recall periods, missing‑data rules, interpretation, and fit‑for‑purpose use in clinical research.

  • Strong, demonstrable experience interpreting and applying scoring methodologies for clinical outcome assessments, including at least some experience beyond simple sum or average scoring.

  • Demonstrable experience translating scientific source materials into structured documentation, specifications, reports, or implementation guidance.

  • Ability to evaluate ambiguous or incomplete source documentation and make sound, well‑documented scientific judgements or escalations.

  • Strong stakeholder management skills and ability to work across scientific, operational, quantitative, and technical teams.

  • Excellent written English and strong documentation discipline.

  • Experience supporting regulated or audit‑sensitive clinical research workflows.

  • Experience supervising or reviewing work from more junior scientists, analysts, or cross‑functional partners.

  • No visa sponsorship available.

  • CV must be submitted in English.


Core Competencies


Demonstrates expertise in COA evaluation and implementation, with a strong focus on scoring methodology, instrument documentation, and psychometric principles. Proven ability to translate scientific requirements into actionable documentation and collaborate effectively across multidisciplinary teams.


Highest‑signal resume keywords



  • COA Science Expertise

  • Scoring Methodology Interpretation

  • Instrument Development Experience

  • Stakeholder Management Skills

  • Advanced Degree in Relevant Discipline


Hard Skills



  • Measure Development

  • Instrument Documentation

  • Scoring Methodology

  • Psychometric Evidence

  • Data Handling Rules

  • Statistical Analysis

  • Documentation Specifications

  • Clinical Outcome Assessments

  • Missing‑Data Rules

  • Interpretation Guidance


Soft Skills



  • Strong Communication Skills

  • Collaboration

  • Problem‑Solving

  • Attention to Detail

  • Leadership


Industry Keywords



  • Clinical Research

  • Patient‑Centered Research

  • Pharma

  • CRO

  • Healthcare Research

  • Outcomes Research

  • Psychometrics

  • Epidemiology

  • Health Sciences

  • Regulated Workflows

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Senior COA Scientist, Scoring & Interpretation Arbeitgeber: Jobtailor

Als Front Office Supervisor in unserem dynamischen Team bieten wir Ihnen die Möglichkeit, in einem unterstützenden und freundlichen Arbeitsumfeld zu wachsen. Wir legen großen Wert auf die berufliche Entwicklung unserer Mitarbeiter und bieten regelmäßige Schulungen sowie die Chance, Verantwortung zu übernehmen. Unsere Lage ermöglicht es Ihnen, Teil einer lebendigen Gemeinschaft zu sein, während Sie gleichzeitig die Standards unseres Franchise-Partners einhalten und unseren Gästen einen unvergesslichen Aufenthalt bieten.

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