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- Aufgaben: Join our team to explore peptide-based molecules and their cell penetration mechanisms using Molecular Dynamics simulations.
- Arbeitgeber: The FMP is a leading research institute in molecular pharmacology, part of the prestigious Leibniz association.
- Mitarbeitervorteile: Enjoy a friendly work atmosphere, excellent infrastructure, and opportunities for professional development and family support.
- Warum dieser Job: This role offers hands-on experience in cutting-edge research and collaboration with top scientists globally.
- Gewünschte Qualifikationen: Candidates should have a Master’s in chemistry, biochemistry, or bioinformatics, with skills in molecular modeling.
- Andere Informationen: We value diversity and encourage applications from all backgrounds, including those with disabilities.
Das voraussichtliche Gehalt liegt zwischen 36000 - 60000 € pro Jahr.
The Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) belongs to the Forschungsverbund Berlin e. V. (FVB) . The FVB is an institution of seven natural sciences research institutes in Berlin funded by the Federal Republic of Germany and the association of its federal states. The research institutes belong to the Leibniz association.
The FMP in Berlin is a non-university research institute that conducts basic research in molecular pharmacology and provides a vibrant and collaborative environment with state-of-the-art facilities for research and employees from all over the world.
The research unit Structural Chemistry & Computational Biophysics , led by Prof. Han Sun, is looking for a PhD student (f/m/d) (Ref. 14/2024) .
The position will start on April 1, 2025 and is initially limited to 3 years with the potential for extension.
Project description:
Peptide-based natural and synthetic molecules represent a crucial drug class for the treatment of various diseases. Unlike small molecules, peptides often exhibit high affinity and specificity for their targets but typically suffer from limited cell permeability. In contrast, cyclic peptides, compared to their linear counterparts, demonstrate improved oral bioavailability and cell-penetrating properties. The goal of this project is to elucidate the mechanism of cell penetration by cyclic peptides and the translocation mechanism of peptide-based antibiotics through membrane channels using Molecular Dynamics (MD) simulations. A key objective is to develop innovative computational methods to enhance our atomistic understanding of the membrane transport processes involving peptides.
The recruited PhD student will join the research training group on bioactive peptides (SynPepBio, ) and pursue their PhD at the FMP and the Technical University of Berlin. They will benefit from exceptional training opportunities in peptide research and actively collaborate and engage with other researchers within SynPepBio.
Your profile:
We are seeking a highly motivated, ambitious, and talented young student to join our enthusiastic and collaborative team in an outstanding scientific environment for research. The successful candidates should possess a Master’s degree in chemistry, biochemistry, or bioinformatics and have experience or a solid understanding of molecular modelling and molecular dynamics simulations . Candidates with additional experience in peptide chemistry or natural products are strongly encouraged to apply.
We offer:
- A stimulating environment within a pleasant and friendly working atmosphere, supported by excellent infrastructure
- Employment with all benefits associated with the public service
- Opportunities to work with leading natural product and peptide chemists from around the world
- Participation in first-class conferences and workshops
- Family services and support
Salaries will be based on the TVöD scale. The institute was awarded the certificate of the audit Beruf und Familie as a family-friendly employer. We offer equal opportunities regardless of gender and welcome applications from disabled candidates. They will be preferred in case of equal qualification. We welcome applications from all backgrounds.
For more information please contact:
Prof. Han Sun; E-mail: Homepage FMP:
How to apply:
On the FMP homepage please go to “Stellenangebote/Jobs” and click first on this advertisement and then “Apply online” .
Please send your application including motivation letter, CV, names and contacts of two references and copies of degree certificates as soon as possible but not later than January 31, 2025 .
We are looking forward to your application!
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PhD student (f/m/d) 22. Nov. 2024 Arbeitgeber: Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V.
Kontaktperson:
Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. HR Team
StudySmarter Bewerbungstipps 🤫
So bekommst du den Job: PhD student (f/m/d) 22. Nov. 2024
✨Tip Number 1
Familiarize yourself with the research work of Prof. Han Sun and the SynPepBio group. Understanding their recent publications and ongoing projects will help you tailor your discussions during the interview and show your genuine interest in their work.
✨Tip Number 2
Engage with the scientific community by attending relevant conferences or workshops focused on molecular pharmacology and peptide chemistry. Networking with professionals in the field can provide valuable insights and potentially lead to recommendations.
✨Tip Number 3
Brush up on your skills in molecular modeling and molecular dynamics simulations. Consider working on a small project or simulation that you can discuss during your interview to demonstrate your practical experience and problem-solving abilities.
✨Tip Number 4
Prepare thoughtful questions about the PhD program and the research environment at FMP. This not only shows your enthusiasm but also helps you assess if the position aligns with your career goals and interests.
Diese Fähigkeiten machen dich zur top Bewerber*in für die Stelle: PhD student (f/m/d) 22. Nov. 2024
Tipps für deine Bewerbung 🫡
Understand the Research Focus: Familiarize yourself with the research unit Structural Chemistry & Computational Biophysics and the specific project on cyclic peptides. This will help you tailor your motivation letter to align with their goals.
Craft a Strong Motivation Letter: In your motivation letter, clearly express your passion for molecular pharmacology and your interest in peptide research. Highlight any relevant experience in molecular modeling and dynamics simulations.
Prepare Your CV: Ensure your CV is up-to-date and emphasizes your academic achievements, relevant skills, and any research experience. Include specific projects or coursework related to chemistry, biochemistry, or bioinformatics.
Gather References: Select two references who can speak to your academic abilities and research potential. Make sure to inform them in advance and provide them with context about the position you are applying for.
Wie du dich auf ein Vorstellungsgespräch bei Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. vorbereitest
✨Understand the Research Focus
Make sure you have a solid grasp of the research unit's focus on peptide-based molecules and their mechanisms. Familiarize yourself with recent publications from Prof. Han Sun and the SynPepBio group to demonstrate your genuine interest and knowledge during the interview.
✨Showcase Your Technical Skills
Be prepared to discuss your experience with molecular modeling and molecular dynamics simulations in detail. Highlight any relevant projects or coursework that showcase your skills, especially if you have worked with peptide chemistry or natural products.
✨Prepare Thoughtful Questions
Think of insightful questions to ask about the research environment, collaboration opportunities, and training programs available at the FMP. This shows your enthusiasm for the position and helps you assess if it's the right fit for you.
✨Emphasize Collaboration and Teamwork
Since the position involves working within a collaborative team, be ready to share examples of how you've successfully worked in teams before. Highlight your ability to communicate effectively and contribute positively to a group dynamic.
