PhD candidate (f/m/x) in Immune-Metabolic Research

Full time, 39 hrs./week in Munich.

Overview

Helmholtz Munich develops groundbreaking solutions for a healthier society.

Institute for Metabolism and Immunology (IMI) focuses on how the immune system interacts with metabolism, especially regulatory T cells (Tregs) in type 1 diabetes and other metabolic diseases.

• Position
• We are seeking a

Ph D candidate (f/m/x) to investigate the interface of immunology and metabolism, concentrating on Tregs and their role in type 1 diabetes, type 2 diabetes, and obesity.

Responsibilities

• Investigate tissue‑specific mechanisms of Treg adaptation and dysfunction in metabolic disease, including immune‑metabolic crosstalk in peripheral tissues.
• Drive in vivo research in genetically engineered mouse models to decode Treg biology in metabolically active tissues (pancreas, muscle, adipose tissue).
• Orchestrate immune profiling of T cells — with a sharp focus on Tregs — using multicolor FACS to reveal functional states and hidden phenotypes.
• Build cutting‑edge in vitro systems to uncover how Tregs adapt, specialize, and break down in metabolic disease.
• Shape experimental strategy, turn data into insight, and communicate discoveries in lab meetings, international conferences, and high‑impact publications.
• Work in a fast‑paced, highly collaborative, interdisciplinary environment to develop translational models and pioneering strategies to reprogram immune responses in metabolic disease.
• Profile
• MSc degree in Immunology, Molecular Biosciences or a closely related life science field.
• Strong interest in cellular immunology with a deep focus on T cells and Treg biology.
• Hands‑on experience with in vivo mouse models (FELASA certification is a strong plus).
• Practical experience in flow cytometry (FACS), including protocol establishment, optimization, and troubleshooting for robust outcomes.
• Computational and digital research skills, including RNA‑seq data analysis, R‑based statistical analysis and visualization, scientific documentation (Microsoft Office), and general computational proficiency.
• Independent, solution‑oriented thinker with a collaborative mindset — scientifically bold, motivated, and translationally oriented.

Benefits

• Career Development: Postdoc program, scientific training & career center with tailored offers.
• Scientific Resources: State‑of‑the‑art infrastructure and Core Facilities.
• Recreation: 30 days annual leave, flexi days, plus public holidays.
• International Staff Service: Support with the relocation and integration process in Germany.
• Health Promotion: Sports, company doctor, mental health initiatives.
• Postdoctoral and career counseling support.
• Managing
• Director
• Mike

Frieser: "We believe that diversity is the key to groundbreaking research and innovative solutions.

Our flexible working models and remote options create a supportive environment for balancing work and family life.

For us, contributing to a healthier society in such an inspiring workplace is truly meaningful."

Our commitment to diversity: We welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age.

Qualified applicants with physical disabilities will be given preference.

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