Head of Process Development

Founded in 2004 by a group of PhD students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 160 highly qualified employees. In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin therapeutics. The continuous development of a broad portfolio of therapeutic product candidates in oncology, radio-ligand therapy and ophthalmology based on the company’s proprietary DARPin platform allowed a successful listing of the company on the SIX Swiss Exchange and Nasdaq (ticker: MOLN). Next to our own pipeline of drug candidates we have entered into collaborations with leading international pharmaceutical companies, including AbbVie, Amgen, Oranomed and Novartis. Our highly dedicated, multi-disciplined team is committed to bringing novel, life‑changing treatments to patients by leveraging our innovative technology platform. We seek passionate, creative, and dynamic individuals to join our mission to transform the therapeutic landscape.

Role & Responsibilities

To strengthen our CMC organization and support the advancement of our growing pipeline, we are seeking an experienced Head of Process Development (Director). In this leadership role, you will be responsible for defining and driving end‑to‑end process development strategies across upstream (USP) and downstream (DSP) for DARPin therapeutics. You will lead internal teams and collaborate closely with external CDMOs to ensure the development of robust, scalable and compliant manufacturing processes from early development through GMP production. You will oversee technology transfers, GMP manufacturing activities, and contribute to regulatory submissions, while ensuring high‑quality material supply for preclinical and clinical studies.

Qualifications

• PhD in Biotechnology, Biochemistry, Chemistry, Chemical Engineering, or a related field;
• Extensive experience in biologics process development, covering downstream processing and ideally upstream processing;
• Deep expertise in protein purification, process development, and scale‑up;
• Proven experience in technology transfer to CDMOs and oversight of GMP manufacturing campaigns;
• Strong experience working in a GMP‑regulated environment, including batch record review, deviations and change control;
• Proven leadership experience in building and leading high‑performing teams within matrix (e.g. CMC team) and line management structures;
• Strong analytical and problem‑solving skills with a hands‑on scientific mindset;
• Excellent organizational and communication skills, with experience in authoring technical and regulatory documentation;
• Collaborative mindset and ability to work effectively in cross‑functional teams;
• Fluent in English (written and spoken).

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