Summary Novartis Biomedical Research Postdoctoral Fellowship Program is a unique training opportunity designed for exceptional early‑career scientists eager to tackle some of the most challenging problems in biomedical research and drug discovery.
Location Basel, Switzerland
Duration 3 years
Program start date October 1, 2026
Application deadline July 15, 2026 EOB
About The Role As a Postdoctoral Research Fellow you will join Discovery Sciences in Basel, a multidisciplinary research department advancing target discovery and translational research through innovative science and technology, and pursue an innovative research project at the forefront of biomedical science and drug discovery.
Our fellows are empowered to ask bold scientific questions, apply cutting‑edge technologies, and develop approaches that have the potential to transform patient care.
Research Opportunity Inflammatory bowel disease (IBD) remains a significant unmet medical need. This project aims to advance our understanding of mechanisms that influence intestinal tissue function and inflammatory processes by leveraging innovative human‑derived experimental systems.
The postdoctoral fellow will develop and apply state‑of‑the‑art human organoid and cellular models together with molecular and cellular biology approaches to investigate disease‑relevant mechanisms regulating intestinal tissue function and inflammation. These models will be used to improve disease understanding, enable mechanistic studies, and support the discovery and validation of novel therapeutic targets. Working within a highly collaborative and multidisciplinary environment, the fellow will generate insights that contribute to the identification of new therapeutic opportunities for patients with IBD.
Key Responsibilities
Establish human intestinal organoid and epithelial barrier models for IBD research
Develop assays assessing barrier integrity, inflammatory responses, and multi‑omics profiles
Implement CRISPR‑Cas9 genetic perturbations in organoid systems to investigate gene function and validate therapeutic target hypotheses
Execute medium‑throughput functional screening of IBD‑associated genetic risk factors
Identify and prioritize novel therapeutic targets based on genetic risk factors and functional screening data
Drive experimental design, data interpretation, and project advancement
Analyze and interpret experimental and molecular datasets
Collaborate closely with scientists across departments
Present research findings internally and externally, and drive the preparation and publication of scientific manuscripts
Essential Requirements
PhD (or equivalent doctoral degree) in cell biology, molecular biology, immunology, genetics, bioengineering, biomedical sciences, or a relevant scientific discipline completed prior to the fellowship start date. The program is intended for scientists immediately following their PhD training (graduated in 2026)
Demonstrated record of scientific achievement (publications, presentations, patents, or equivalent)
Experience with complex mammalian cell culture systems, such as organoids, stem‑cell‑derived models, or epithelial tissue models
Strong experimental skills in molecular and cellular biology
Interest in disease mechanisms, translational research, advanced human in vitro models, and the integration of human genetic and single‑cell omics data
Ability to work effectively in a multidisciplinary and collaborative environment
Strong communication, presentation, and scientific writing skills
Strong commitment to learning, innovation, and professional development
Desirable Requirements
Experience with CRISPR‑based genome engineering
Experience developing functional assays in complex intestinal models
Postdoctoral Fellows Benefit From
Guidance from accomplished scientific leaders and subject matter experts
Access to advanced technologies, platforms, and research capabilities
Collaboration across disciplines and organizational boundaries
A global and diverse community of postdoctoral fellows
Dedicated development programs designed to help fellows thrive throughout their careers
Personalized experiential learning opportunities through a Postdoc Practicum that empowers fellows to explore new scientific domains, build cross‑functional expertise, and expand their impact beyond their primary research project
Opportunities to present research, publish in leading journals, and build an international scientific network
How to Apply Submit your CV and cover letter by July 15, 2026 end of day. In your cover letter describe your research interests, career aspirations, and how participation in the Novartis Biomedical Research Postdoctoral Fellowship Program will support your long‑term development. Confirm your availability to meet the October 1, 2026 start date. Applicants must be eligible to work in Switzerland.
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Location Basel, Switzerland
Duration 3 years
Program start date October 1, 2026
Application deadline July 15, 2026 EOB
About The Role As a Postdoctoral Research Fellow you will join Discovery Sciences in Basel, a multidisciplinary research department advancing target discovery and translational research through innovative science and technology, and pursue an innovative research project at the forefront of biomedical science and drug discovery.
Our fellows are empowered to ask bold scientific questions, apply cutting‑edge technologies, and develop approaches that have the potential to transform patient care.
Research Opportunity Inflammatory bowel disease (IBD) remains a significant unmet medical need. This project aims to advance our understanding of mechanisms that influence intestinal tissue function and inflammatory processes by leveraging innovative human‑derived experimental systems.
The postdoctoral fellow will develop and apply state‑of‑the‑art human organoid and cellular models together with molecular and cellular biology approaches to investigate disease‑relevant mechanisms regulating intestinal tissue function and inflammation. These models will be used to improve disease understanding, enable mechanistic studies, and support the discovery and validation of novel therapeutic targets. Working within a highly collaborative and multidisciplinary environment, the fellow will generate insights that contribute to the identification of new therapeutic opportunities for patients with IBD.
Key Responsibilities
Establish human intestinal organoid and epithelial barrier models for IBD research
Develop assays assessing barrier integrity, inflammatory responses, and multi‑omics profiles
Implement CRISPR‑Cas9 genetic perturbations in organoid systems to investigate gene function and validate therapeutic target hypotheses
Execute medium‑throughput functional screening of IBD‑associated genetic risk factors
Identify and prioritize novel therapeutic targets based on genetic risk factors and functional screening data
Drive experimental design, data interpretation, and project advancement
Analyze and interpret experimental and molecular datasets
Collaborate closely with scientists across departments
Present research findings internally and externally, and drive the preparation and publication of scientific manuscripts
Essential Requirements
PhD (or equivalent doctoral degree) in cell biology, molecular biology, immunology, genetics, bioengineering, biomedical sciences, or a relevant scientific discipline completed prior to the fellowship start date. The program is intended for scientists immediately following their PhD training (graduated in 2026)
Demonstrated record of scientific achievement (publications, presentations, patents, or equivalent)
Experience with complex mammalian cell culture systems, such as organoids, stem‑cell‑derived models, or epithelial tissue models
Strong experimental skills in molecular and cellular biology
Interest in disease mechanisms, translational research, advanced human in vitro models, and the integration of human genetic and single‑cell omics data
Ability to work effectively in a multidisciplinary and collaborative environment
Strong communication, presentation, and scientific writing skills
Strong commitment to learning, innovation, and professional development
Desirable Requirements
Experience with CRISPR‑based genome engineering
Experience developing functional assays in complex intestinal models
Postdoctoral Fellows Benefit From
Guidance from accomplished scientific leaders and subject matter experts
Access to advanced technologies, platforms, and research capabilities
Collaboration across disciplines and organizational boundaries
A global and diverse community of postdoctoral fellows
Dedicated development programs designed to help fellows thrive throughout their careers
Personalized experiential learning opportunities through a Postdoc Practicum that empowers fellows to explore new scientific domains, build cross‑functional expertise, and expand their impact beyond their primary research project
Opportunities to present research, publish in leading journals, and build an international scientific network
How to Apply Submit your CV and cover letter by July 15, 2026 end of day. In your cover letter describe your research interests, career aspirations, and how participation in the Novartis Biomedical Research Postdoctoral Fellowship Program will support your long‑term development. Confirm your availability to meet the October 1, 2026 start date. Applicants must be eligible to work in Switzerland.
#J-18808-Ljbffr
Discovery Postdoctoral Fellow – Inflammatory Bowel Disease Research Arbeitgeber: Novartis
Novartis ist ein hervorragender Arbeitgeber, der seinen Mitarbeitern in Basel, Schweiz, eine dynamische und innovative Arbeitsumgebung bietet. Mit einem starken Fokus auf Mitarbeiterentwicklung und einer Kultur der Zusammenarbeit ermöglicht das Unternehmen seinen Angestellten, ihre Fähigkeiten im Bereich KI und Technologie strategisch auszubauen. Die flexiblen Arbeitsoptionen und leistungsorientierten Boni machen Novartis zu einem attraktiven Arbeitsplatz für alle, die eine sinnvolle und lohnende Karriere anstreben.
