Vice President, Head of Europe Medical Affairs

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Reporting to the Senior Vice President (SVP) Head of Europe, the Vice President & Head of Europe Medical Affairs will lead the development and execution of RevMed’s Medical Affairs strategy across the European Region, ensuring alignment with global objectives and local needs. This leadership role is critical to maximizing the opportunity for RevMed Innovation to impact patients across the region. In collaboration with the SVP Head of Europe and the SVP Head of Global Medical Affairs, the successful medical leader will develop and execute comprehensive regional medical strategies to accelerate engagement with European key stakeholders (government authorities, regulatory authorities, payer authorities, physicians). This leader will ensure that regional medical considerations are embedded in the global medical strategy and plans and will partner with the SVP Head of Europe and their leadership team including GMs and their country medical affairs and market access teams to ensure that reimbursement and access considerations are integrated in the existing and future clinical program design of the company portfolio/pipeline. The incumbent will be responsible for building and leading the European medical affairs team and working closely with the Country Medical Affairs teams across Med Affairs functions including Med Info, Pharmacovigilance & HEOR.

Responsibilities:

• Lead the development and execution of the European Medical Affairs strategy for RevMed’s portfolio, ensuring alignment with global objectives and local market needs.

• As directed by the commercialization strategy, build and lead the European Medical Affairs team, working with cross-functional leaders to ensure that each team member and function executes against the clear and well-aligned business objectives.

• Serve as the regional medical expert across the oncology portfolio, providing guidance and close partnership with clinical development, clinical operations, market access, regulatory strategy, and commercialization plans.

• Work with the global team to drive regional scientific communication activities, including publication planning, congress strategy, and development of medical education programs.

• Provide medical insight and leadership on cross-functional teams, including Global Medical Affairs, Europe Regulatory Affairs, Clinical Development & Clinical Operations, Commercial, Market Access, and Safety.

• Ensure all medical activities adhere to ethical, regulatory, and compliance standards.

• Support the medical review of promotional materials and contribute to internal training and capability building for oncology medical teams.

• Develop and manage the Europe Region Medical Affairs budget, in alignment with the SVP, Head of Europe.

• Foster a culture consistent with the global RevMed values and vision/mission.

Clinical Collaboration in line with regulatory/compliance requirements:

• Collaborate with US and global teams to initiate and support clinical trials in Europe, ensuring adherence to regulatory guidelines and timelines.

• Work closely with clinical operations, medical affairs, market access, and regulatory teams to facilitate smooth startup and execution.

• Provide strategic input to global teams in the US on the selection of endpoints, comparators, patient populations, and study designs to ensure clinical trials generate meaningful data.

• Support the groundwork for Phase I-III clinical trials by identifying potential clinical trial sites, establishing relationships with investigators, and supporting preparation of regulatory submissions.

Establish and maintain collaborative relationships with Key Opinion Leaders (KOLs), academic institutions, cooperative groups, professional societies, and healthcare providers

• Develop and maintain strong relationships with Key Opinion Leaders (KOLs) in the field of pancreatic and lung cancer.

• Engage with KOLs to gather insights, validate clinical development plans, and support market development activities.

• Leverage KOL relationships to enhance the company\\\’s scientific and commercial credibility in European markets.

• Build and maintain relationships with other key stakeholders, including healthcare professionals and organizations, country and region regulatory bodies, patient advocacy groups, and industry partners.

• Facilitate effective communication between internal teams and external partners to align goals and expectations.

• Represent the company at international and European conferences, industry events, and regulatory meetings to promote our cell therapy products and company mission.

Collaborate to support European Market Access/Early Access Programs

• Oversee medical input into HTA submissions, payer engagement strategies, and external expert consultations to support market access and reimbursement.

• Lead planning and development of expanded access programs in the region, as appropriate.

• Provide regional input into the design of Real-World Evidence (RWE) initiatives, Phase IV studies, and Investigator-Sponsored or Collaborative Research.

Required Skills, Experience and Education:

• Advanced scientific degree required (MD, PhD, or PharmD) with a specialization or significant experience in oncology.

• Minimum 10 years of relevant experience in Medical Affairs within oncology, including regional or global leadership roles.

• Proven ability to lead medical strategy and engage effectively with external oncology experts and stakeholders.

• Demonstrated ability to build and lead a high-performing medical affairs team.

• Strong leadership and influencing skills with the ability to create a clear sense of direction.

• Strong knowledge of the European oncology landscape, including regulatory frameworks, treatment guidelines, and reimbursement pathways.

• Experience with scientific data generation, clinical trial interpretation, and communication of complex data to diverse audiences.

• Ability to create and nurture a strong culture of collaboration and authenticity to extend and replicate the RevMed culture at the regional level.

• Highly organized and motivated individual possessing excellent communication, presentation and interpersonal skills.

• Strong team orientation and passion for continuous self and team development.

• Ability to flexibly lead; willingness to learn new therapeutic areas and technologies.

• Thrives in a fast-paced, dynamic small company environment and able to adjust priorities and workload based upon changing needs.

Preferred Skills:

• Experience with oncology launches is desired.

• Experience in gastrointestinal and lung cancers preferred.

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