Junior Group Leader, Computational Biology

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The Position

This job posting is for the role of Junior Group Leader in Computational Biology. We are looking for an innovative scientific mind to establish an independent research program within our new Computational Biology Core at the Institute of Human Biology (IHB). This is a unique opportunity to launch your career as a principal investigator, shape your research vision, and make meaningful contributions to human biology in a dynamic and interdisciplinary environment.

The Opportunity

As a Junior Group Leader, you will have the freedom to conduct innovative research while benefiting from a collaborative and well-supported environment. In this role, you will:

• Establish and lead an independent research program in computational biology. The primary focus for this group would be computational morphometry of human model systems. Applications for other areas of computational biology, such as integration of multi-modal, large-scale data sets and causal inference are of interest as well.

• Collaborate with world-class academic institutions (like ETH Zürich and EPF Lausanne) and global biopharma leaders (including Roche\’s pRED (Pharma Research and Early Development) and Genentech).

• Leverage state-of-the-art platforms, technologies, and Roche’s core facilities to advance your research.

• Mentor and guide graduate students through our joint PhD programmes.

• Contribute to a culture that translates scientific discoveries into transformative medicines for fields like Immunology, Neurology, and Oncology.

• Leverage a highly competitive funding package to support your team and research goals.

• Shape the future of translational research by bridging the gap between academic and pharmaceutical science.

Who You Are

We are looking for a creative and passionate leader with a proven record of groundbreaking research. We believe you will be successful in this role if you:

• Have recently completed a successful postdoctoral appointment and are eager to launch your career as a principal investigator.

• Possess a strong track record of innovation in computer vision, AI, and/or causal inference, with a passion for applying these to human model systems.

• Exhibit extraordinary leadership potential and a desire to advance scientific inquiry within collaborative teams.

• Are driven to translate discoveries into transformative medicines through collaboration with our scientists and partners.

• Thrive in an interdisciplinary environment, working alongside biologists, engineers, and other computational scientists.

The position is fully funded for 5 years, supporting a group size of 4 members plus 1 PI.

Join us at IHB, where your passion and expertise will help shape the future of medicine and make a real difference in people\’s lives.

IHB Fast Facts

IHB website:
IHB Director: Hans Clevers
CoDirectors: Gaudenz Danuser, Marianne Manchester, Matthias Lutolf, Daniele Soroldoni
Planned Size: >150 researchers
IHB platforms and expertise: Single-cell genomics, Microtechnologies, Bioengineering, High-throughput imaging, CRISPR-gene editing, Biobanking, Automation, Applied translation support
Core facilities: Fluorescent microscopy, Genomics and high-throughput sequencing, Flow cytometry and cell sorting, Proteomics/Metabolomics, Information technology

Computational facilities: Full access to and collaboration with Roche\’s world-class global computational infrastructure, computational science groups/network/community, and data platforms.
PhD programs: Department of Biosystems Science and Engineering, ETH Zürich

Questions can be directed to:

Please submit your application by August 25 (CET), 2025, at the latest and directly on the Roche careers portal. Applications submitted via email will not be considered.

Application Documents:

• Research statement (2-page summary of previous research, 3-page overview of research vision and plan)

• CV

• Contact information for three references

Finalists will be invited for a recruitment symposium in September/October.

Basel Hub and Campus Switzerland

Basel is an international hub for research and innovation. The University of Basel, Department of Biosystems Sciences and Engineering of the ETH Zürich, Friedrich Miescher Institute for Biomedical Research, Swiss Tropical and Public Health Institute, University Hospital Basel, and Institute of Human Biology, nurture training environments for basic science learning and exploration. Together with headquarters and research innovation centers for world-leading pharmaceutical companies and biotechnology startups, the city is a melting pot of research, development, and commercialization. IHB has ongoing collaborations with many relevant and internationally recognised organisations, for example, the BioVision Center at the University of Zurich.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.

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