Head of Pharmacology (m/w/d) in Großmehring, München

At smartbax, we aim to introduce the next generation of antibiotics.Founded in 2021,we develop novel antibacterial compounds with extraordinary potency against multi-drug resistant bacteria and hijack bacterial pathways that no other drug has touched before. As a start-up in Munich’s vibrant biotech scene, we offer an environment where your work makes a real difference.Help us pioneer new therapies that will save lives. We are looking for a Head of Pharmacology with proven expertise in preclinical antibiotic development to move our pipeline successfully to IND/CTA filing. Your tasks Co-lead the DMTA cycle side-by-side with our Head of Medicinal Chemistry Coordinate DMPK/ADME, PK/PD and in vivo efficacy testing, including management and orchestration of corresponding CROs Prepare the preclinical safety and IND/CTA-enabling data package, including communication with regulators, and lay the scientific and strategic groundwork for subsequent clinical studies Evaluate, visualise and present data towards the team, shareholders and investors Support the management in fundraising and company representation Lead and guide the scientific team with your experience, define and delegate responsibilities, and foster the personal growth of each team member as well as the company as a whole Your profile >10 years experience in industrial drug discovery and development at Director / Senior Director / Head/ VP level, preferably also in startup environments Personally carried at least one small molecule from late lead optimization through IND/CTA filing Proven track record in the AMR field - antibacterial PK/PD fluency is a must Strong global network with CROs and regulators Direct experience in drug development against Enterobacterales / UTI and strong connections into the AMR non-dilutive ecosystem (CARB-X, GARDP) are a significant plus Fast and critical thinker, not hesitant to make decisions under time pressure and with imperfect data Self-organised, enjoys working in small teams Proficient in written and spoken English We offer Purpose: Contribute to the fight against antimicrobial resistance, one of the greatest healthcare challenges of our time Freedom and agility: Flat hierarchy, fast decision making, and no unnecessary bureaucracy, allowing you to focus on things that really matter Shaping the company’s future: Core position with direct impact and strategic influence in a highly motivated and experienced team A workplace tailored to your needs: Flexible working hours, brand-new lab and office spaces, and the freedom to work from home when needed, including the option for a hybrid on-site/remote model An ecosystem designed for success: Join a cutting-edge biotech start-up in Munich with strong backing from venture capital and family offices across the pharma sector Start: Q1 2027 | Location: Munich/Neuherberg (Life Science Factory at the Helmholtz Pioneer Campus) #J-18808-Ljbffr