Postdoc (all genders) in intestinal immunity / section Regenerative Medicine and Immunology

Making an Impact in Translational Medicine. Dr. Dimitra Z.: Physician Scientist and future leader. At the University Medical Center Hamburg-Eppendorf (UKE), we are committed to excellence in research, education, and comprehensive healthcare across our clinics. Our goal is to be one of the leading university hospitals while auch being the best employer in our industry.

At UKE, we believe that meaningful and successful work should align with our employees' personal needs and individual lifestyles. Just as diverse as these needs are, so too is the variety of personalized solutions we offer.

Main tasks:

• CD4+ T cells are key regulators of host-defense against pathogens, more recent studies by our group have shown that CD4+ T cells importantly regulate tissue (re)generation in humans.
• During the lifespan, the immune system faces time-window dependent challenges characterized by changes in microbial and virus exposure and tissue growth, resulting in an increased risk of infectious and immune-mediated diseases e.g. early in life and adolescence, especially upon exposure to infectious, metabolic or endocrine stressors.
• In this project, the role of endocrine dysregulation in disruption of fetal organ immune development through epigenetic modifications and subsequent susceptibility of inflammatory bowel disease are investigated.
• The studies build on analyses of observational studies including several single cell omics and computational analyses and innovative human intestinal tissue-based organoid systems to decipher the molecular interactions between immune cells and parenchymal cells in tissue (re) generation and inflammation.
• The goal is to understand critical developmental programs regulating intestinal immune development and identify pathways that can be targeted to restore tissue homeostasis.

Your tasks:

• Experimental studies of intestinal organoid systems and immune cells, including planning of experimental design, experiments, documentation and statistical analysis of results; interpretation, discussion and presentation of results.
• Computational analyses of high dimensional data, including flow cytometry, scRNAseq and spatial transcriptomics.
• Scientific publishing, presentation at international conferences, community outreach.

Your Profile:

• Completed scientific university degree and preferably a PhD in biology, biochemistry, or a related field, or a medical degree with a clinical-scientific background.
• Training in (tissue) immunology or infectious diseases.
• Expertise in computational analyses of various OMICS data sets.
• 2 letters of recommendation from former mentors.
• Strong interest in pursuing research in academia.

We look much forward to receiving your application, including CV, publication list, and certificates recommendation letters.

Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.

Our Offer:

• Fair and transparent compensation in accordance with our collective bargaining agreement (TVöD/VKA / TV-Ärzte/VKA) (€ 63,600 - € 91,100), taking into account qualifications and professional experience.
• Targeted and individualized professional development at both the technical and project levels is provided, offering long-term prospects in a meaningful work environment.
• Comprehensive continuing education and training programs at UKE Academy for Education and Career.
• Opportunities to help shape our “UKE INside” personnel policy through cross-functional and cross-hierarchical projects.
• Sustainable commuting: Subsidies for the Deutschlandticket as a job ticket and Dr. Bike bicycle service.
• Excellent health, prevention, and sports programs.
• Family-friendly work environment: Partnerships for childcare, free vacation care, counseling for employees with family members requiring care.
• A secure job, meaningful work, and a supportive team environment.
• Structured onboarding and open knowledge sharing within the team.
• Our employee restaurant offers a wide variety of culinary options; additional options are available at the “Health Kitchen” cafés and bistros and at a supermarket located directly on the premises.

We look forward to receiving your application by 01.09.2026.

Contact:

Contact to the department: Prof. Dr. Bunders m.bunders@uke.de

We live diversity and value variety. We offer a work environment that provides equal opportunities regardless of age, gender, sexual identity, disability, ethnic and social origin, or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under-representation of one gender in the advertised area. Persons with severe disabilities with equal aptitude, competence, and professional performance will be given priority.